It works just like it does in other apps or even on Windows. Move to where you want to begin selecting with VoiceOver, then just hold down shift and use the arrow keys to extend the selection as if you were in a text field, then you just command+C to copy when you’re done. Also, quicknav has to be off in VoiceOver while you’re doing this.

@pitermach Thanks - It seems to be an Edge issue. If I do that in Safari, it is working fine. If I select with my mouse, I can adjust with Shift and arrow keys. Just can’t initiate the selecting.