On my side Microsoft 365 generates NDR when I send the message to non existing email address using outlook online but does not generate NDR when sending a message to same non existing email address from thunderbird or other app sending emails through microsoft 365 SMTP server.
This sounds strange to me and I can't find a way to make it generate NDR aka bounce messages for messages submitted through SMTP.
in reply to Peter Vágner

Oh, those NDR message are actually generated but they are delivered to spam folder.
Even after disabling backscatter protection under advanced antispam settings it's working like that.
These automatically generated messages can't be manipulated using transport rules, so I have no workaround for this issue.
in reply to Peter Vágner

yeah, it's annoying, I remember one saturday morning when someone from office called me because i forgot to send something. I actually did but by made mistake in email address. Then I realized that I have delivery status notification in spam.