A big month for progress on mucosal Covid vaccines!

- A 35th mucosal vax in clinical trial
- Encouraging preclinical results for intranasal self-amplifying mRNA vax from Spain
- News on progress with the Covid infection studies laying the groundwork for testing mucosal vax in human challenge studies

Plus more clinical results for self-amplifying mRNA vax & fascinating pandemic preparedness news from Singapore

Nextgen Covid vax update @PLOS absolutelymaybe.plos.org/2025/…

#Covid #Covid19 #Vaccines

A Big Month for Progress on Mucosal Covid Vaccination (NextGen Vax Update 33) - Absolutely Maybe

It was a bumper month for mucosal Covid vaccines. There were some phase 1 results for an intranasal vaccine from China: It’s…

^{Hilda Bastian (Absolutely Maybe)}

La COVID n’est pas terminé !

Situation au Québec :

Les plus récentes données sur l’évolution de la COVID‑19, pour la semaine du 14 au 20 septembre 2025, au Québec, font état de : 1 057 nouveaux cas.

Nombre total d’hospitalisations : 519

quebec.ca/sante/problemes-de-s…

#COVID19 #portezunmasque #polQC #QCpoli #cdnpoli #polcan

Données sur la COVID-19 au Québec

Situation au Québec en lien avec la COVID-19 : le nombre de cas, d'hospitalisations, etc. ainsi que les scénarios de l’évolution de la COVID-19.

^{Gouvernement du Québec}

Velmi od pasa¹: mozno novy variant #Covid19

cas.sk/spravy/zahranicne-sprav…

¹ edit: "pun NOT intended", skratka som chcel povedst, ze len hadam na zaklade malo informacii a este menej znalosti

Varovanie! Nový variant covidu má nezvyčajné príznaky

Lekári bijú na poplach. Objavil sa nový variant koronavírusu s názvom NB.1.8.1, ktorý znepokojuje odborníkov.

^{Redakcia Nový Čas (Nový Čas)}

I saw this yesterday and can't stop thinking about it.

#covid #COVID19 #CovidIsNotOver

#COVIDISNOTOVER

A new #COVID19 variant is coming... NB.1.8.1 has been detected in California and other US states, as well as in the eastern Mediterranean, etc. globalnews.ca/news/11201389/co… #WEARAMASK #GETVACCINATED #cdnpoli #polcan #NB181

New COVID-19 variant sees rise in cases in some countries. Here’s where

Airport screening in the United States has detected the new variant in travellers arriving from those regions to destinations in California, Washington, Virginia and New York.

^{globalnewsdigital (Global News)}

The World Health Organization has designated NB.1.8.1 as a SARS-CoV-2 variant under monitoring.

FYI The NB.1.8.1 variant is a member of the #Omicron family... prevention.com/health/health-c… #COVID19 #COVIDISNOTOVER #WEARAMASK #GETVACCINATED #WHO #VUM #NB181 #cdnpoli #polcan

What to Know About the Latest COVID-19 Variant, NB.1.8.1, Spreading Across the Globe

NB.1.81. is the latest COVID-19 variant spreading in the U.S. and Europe. Infectious disease doctors explain NB1.8.1 symptoms, treatment, and prevention.

^{Korin Miller (Prevention)}

Nearly 400 New Brunswick residents suffer from what the province calls a “neurological syndrome of unknown cause...

Unknown cause? Nerve pain/damage, numbness, and necrotizing gingivitis, etc. are all KNOWN #COVID19 complications.

ctvnews.ca/atlantic/new-brunsw… #healthcanada #publichealthcanada

'Good first step': N.B. mystery brain disease patients welcome new investigation

The New Brunswick government has reopened an investigation into a mystery brain disease that seems to mostly affect people living in the Acadian Peninsula and Moncton areas.

^{The Canadian Press (CTVNews)}

My spreadsheet of the longer-term implications of #COVID19 infections has now reached 1,100 studies. Recent additions show COVID and Long COVID causes fatigue, heart arrhythmias, reduced white blood cell count, T-cell exhaustion, lower quality of life, cognitive impairment, insomnia, erectile dysfunction, and persistent liver damage.

docs.google.com/spreadsheets/d…

COVID-19/SARS-CoV-2 Studies

^{Google Docs}

We have reached peak absurdity

#Covid #Covid19

Fortsetzung des Abwassermonitoring, insbesondere, aber nicht nur, für #sarscov2 #COVID19 - bitte hier unterschreiben, das ist eine der letzten Metriken, die wir überhaupt noch haben.

chng.it/QkMvRNbGLV

#amelag #covidisnotover #depol #WasteWaterSurveillance

If you live in the United States, you can now order 4 free COVID-19 tests.

Visit covidtests.gov or special.usps.com/testkits for more details.

#covid #covid19 #CovidTests #FreeCovidTests #health #PublicHealth

Still this so much.

#COVID19 #COVID

Had a mild #COVID19 infection?
Doesn’t mean it’s mild.

#SARS-Cov-2 can behave like HIV or Polio. It can cause internal damage long after apparent recovery.

Mild initial infection does not = mild disease.

Multiple studies show this. #LongCovid
nbcnews.com/health/health-news…

Seems like huge news: "Nasal COVID-19 vaccine halts transmission"

Study in hamsters indicates vaccines targeting nose, mouth may be key to controlling spread of respiratory infections

medicine.wustl.edu/news/nasal-…

#COVID19 #Covid

Nasal COVID-19 vaccine halts transmission | Washington University School of Medicine in St. Louis

^{Tamara Schneider (Washington University School of Medicine in St. Louis)}

Long COVID can change your life--even if you've seemingly recovered. “People who have recovered from long COVID can suffer relapses or flare-ups from new viral infections — not just from COVID but from cold, flu, and other viral pathogens, researchers have found.”

The ONLY way to prevent Long COVID is to avoid your next infection with #COVID19.

medscape.com/viewarticle/cold-…

Cold, Flu Virus Can Trigger Long COVID Relapses

Those who treat and research long COVID warn that viral persistence and reactivation are real risks for some patients.

^{Tinker Ready (Medscape)}

Any #blind people have one of these? Are they accessible. The page says there’s a bluetooth module. Does that mean they have an app where you can get your results accessibly? How is the accessibility of the test kit itself, in terms of a blind person being able to use it without too much difficulty?

shop.aptitudemedical.com/produ…

#Covid #Covid19 #CovidIsntOver

Metrix® COVID-19 Test & Reader Starter Bundle

  The Metrix® Test & Reader Starter bundle gives you everything you need to get started. The bundle includes 2 Metrix® COVID-19 Test Kits and 1 reusable Metrix® Reader.

^{Aptitude Medical Systems}

Do take the time to read this brilliant piece.

It contains excellent explanations on the spread of COVID mutations/variants, why vaccination alone isn't the answer, why we should continue to mask and negative communications.

#WearAMask #WearADamnMask #CovidIsNotOver #COVID19 #covid

open.substack.com/pub/thegaunt…

Does the public understand that "variant" means "vaccine resistant"?

Getting boosted is critical because the virus is changing. Other forms of mitigation are critical to slow the rate of change.

^{Julia Doubleday (The Gauntlet)}

a friend and I were talking about COVID precautions and they just sent me this paper which appears to raise concerns about safety and efficacy of wearing masks for COVID - does anyone here know anything about this paper + what conclusions should be drawn from it? I feel like there's probably *something* wrong with it given it very much is the consensus in communities I'm in (that seem to pay lots of attention to the literature) that wearing masks is a good precaution to take against COVID, but I'm not sure how to respond. is there a good analysis of the paper somewhere or anything like that?

ncbi.nlm.nih.gov/pmc/articles/…

#COVID19 #CovidIsNotOver #WearAMask #covid

Possible toxicity of chronic carbon dioxide exposure associated with face mask use, particularly in pregnant women, children and adolescents – A scoping review

During the SARS-CoV-2-pandemic, face masks have become one of the most important ubiquitous factors affecting human breathing. It increases the resistance and dead space volume leading to a re-breathing of CO[2] .

^{PubMed Central (PMC)}

Ich möchte auch einen umfassenden "gesellschaftlichen Aufarbeitungsprozess".

Warum wurden wir so inkonsequent geschützt? Warum wurde so konsequent aufgegeben? Warum wurde die Intensität der Forschung reduziert? Warum haben wir immernoch nichts gelernt für den Alltag? Warum kein Recht auf Schutz?

Ich bin wütend. Und ich vermute, keine dieser Fragen werden ernsthaft gestellt.

deutschlandfunk.de/virologe-dr…

#covid19 #CovidIsNotOver #depol #drosten #lauterbach #dlf

Vier Jahre nach dem ersten Corona-Lockdown - Virologe Drosten fordert gesellschaftlichen Aufarbeitungsprozess der Pandemie

Vier Jahre nach dem ersten Corona-Lockdown hat der Virologe Christian Drosten einen umfassenden gesellschaftlichen Aufarbeitungsprozess gefordert.

^{Die Nachrichten}

Latest comic: What did we learn from Covid?

#covid #COVID19 #coronavirus #cartoon #health #healthcare #pandemic #comic

The UK government is planning to scrap millions of unused SARS-CoV-2 vaccine doses, which could have been used to vaccinate previously ineligible groups for free, after they closed the autumn booster campaign.

Meanwhile, pharmacies have just been authorised to offer Covid vaccines at a massive £45 a pop, thus excluding the poorest sections of the population.

And the new scheme starts on...yes you've guessed..April 1st.

#Covid19 #Vaccines #NHSPrivatisation

theguardian.com/world/2024/feb…

Pharmacies in England and Scotland to offer private Covid jabs – for £45

Pharmadoctor is offering appointments from 1 April for vaccinations and intends to add more pharmacies to its network

^{Nicola Davis (The Guardian)}

Interesting STUDY on the risks of #COVID19 infection in a university setting in China.

The risk of infection of susceptible students per 45-min lesson was 1%. (That adds up fast with 15 classes/week for many students.)
An occupancy rate of 50% reduced infection risk by 62%.
Fresh air decreased risk by 81.1%.
All students wearing N95 respirators reduced risks by 96%.

So, which of these mitigations are we doing to protect students? None. We are doing none of them.

sciencedirect.com/science/arti…

"Oxygen extraction by the body’s tissues was compromised in patients who had symptoms of #exerciseIntolerance after #COVID"

"Patients are told that their symptoms are a result of deconditioning, or decline from lack of physical activity.
Our findings contradict that hypothesis."

#PostCovid #LongCovid #PEM #MECFS #corona #covid19

news.yale.edu/2023/12/19/study…

Study helps explain post-COVID exercise intolerance

Exercise intolerance is one symptom associated with long COVID. A new study helps explain its cause.

^YaleNews

SARS-CoV-2 attacks the mitochondria in cells, depleting their energy.

"researchers found that the virus blocks specific genes that use oxygen to create ATP, forcing the body to deplete finite energy reserves in the body. Without an energy source, cells throughout the body begin to starve, with the cells powering the brain and the heart suffering the most.”

news.unchealthcare.org/2023/10…

#LongCovid #Covid19

Researchers Show SARS-Cov-2 Infection Affects Energy Stores in the Body, Causing Organ Failure | Newsroom

An international research team, including Jonathan C. Schisler, PhD, in the UNC School of Medicine, has found how SARS-CoV-2 causes widespread “energy outages” throughout major organs, and how these effects contribute to debilitating long COVID sympt…

^{kpdaniel (Newsroom)}

Katalin Karikó and Drew Weissman, who identified a chemical tweak to messenger RNA that laid the foundation for vaccines against #Covid19, were awarded the Nobel Prize in Physiology/ Medicine.

As this photo shows, both scientists are wearing masks and NOT relying on the "vax and relax".

#WearAMask #WearARespirator
#MaskUp #NobelPrize #Covid #CovidIsNotOver #SarsCov2 #COVIDisAirborne

Are you a #sourdough baker? If so, I need your help! I'm researching sourdough baking during the COVID lockdowns for my MA and would love you to fill out my survey!

surveymonkey.co.uk/r/N9MHNF9

I'm also looking for people to tell me about their sourdough baking journey (Yes, even yours!), so if you would be interested, please DM me!

#sourdough #baking #research #COVID19

This is NOT an article from The Onion...

"Several people who attended the Epidemic Intelligence Service Conference have tested positive for COVID-19,” a CDC branch chief wrote in an email to staff on Friday.

#COVID19 #Covid #CovidIsNotOver #CovidIsntOver #CDC

washingtonpost.com/health/2023…

Germany's Corona-Warn-App is being discontinued. Screenshots attached in English and German.

(Die Corona-Warn-App in Deutschland wird eingestellt. Screenshots in Englisch und Deutsch anbei.)

#COVID #COVID19 #Germany #Deutschland #EndOfAnEra #CoronaWarnApp

Want to know WHY there are #NOVIDS?

Masking. Distancing. Not congregating.

READ: Cautious behaviour.

bu.edu/articles/2023/are-you-a…

#COVID19 #WEARAMASK #COVID19ISAIRBORNE

WEAR A MASK.

No one wants masks, but we still need them to keep #COVID19 at bay: theguardian.com/world/2023/feb… #WEARAMASK #COVID19ISAIRBORNE

No one wants masks, but we still need them to keep Covid at bay

Letters: Doctor Kelly Fearnley and an immunocompromised patient respond to Dr Jack Pickard’s letter calling for an end to the requirement for mask-wearing in all clinical areas

^{Guardian staff reporter (The Guardian)}

WEAR A MASK.

#COVID19 subvariant Kraken is spreading in Québec: montrealgazette.com/news/local… #WEARAMASK #WEARINGISCARING #assnat #polQC #polMTL

We'll never fully understand the political agenda that popularized the removal of mask-wearing. It's the least expensive yet most effective way to protect the public.

Mask wearing should never have ended when there is currently over 500 deaths a day.

"WHO backs mask wearing on long flights as new Omicron variant spreads"

yahoo.com/news/1-backs-mask-we…

#COVID19 #CovidIsNotOver #PublicHealth #BringBackMasks #COVIDisAirborne

UPDATE 3-WHO urges travellers to wear masks as new COVID variant spreads

Countries should consider recommending that passengers wear masks on long-haul flights, given the rapid spread of the latest Omicron subvariant of COVID-19...

^{Gabrielle Tétrault-Farber and Natalie Grover (Yahoo News)}

Could reporters stop both-siding COVID and focus on why political leaders are failing us? Politicians aren’t reinstating mandates because masks remind us we are in a pandemic, and they are afraid that people will consume less if they see more people wearing masks. They are prioritizing corporate profits over public health.

washingtonpost.com/health/2022…

#COVID #COVID19 #PublicHealth

NEW: New York City has just issued an advisory for everyone to wear a mask in public spaces because COVID levels are high in all 5 boroughs.

#BringBackMasks #COVID #COVID19 #PublicHealth