If anyone is curious, my current Android setup is as follows:
I use #NeoStore or #Droidify (currently Neo Store, the new stats support is just too tempting) with the #IzzyOnDroid repo as primary app source, the #FDroid repo as secondary.
If I need something not on either of those, I will use #AuroraStore to access #GooglePlay.
Random APKs from GitHub or whatever only in very very specific cases. I will generally wait until the app drops on F-Droid or (preferably) IzzyOnDroid.