Contrary to what many people think, I could adapt #GNOME48 to my particular needs and blogged about my customizations: karl-voit.at/Gnome-Setup/
gsettings is great to reproduce the setup on other machines. 👍
#GNOME shines on simple setups but seems to have some issues when the setup gets a bit more complex.
Furthermore, speed was an issue at my side: I was a heavy user of invoking the GNOME shell for starting applications and switch windows but unfortunately that was a bit of a drag to be honest.
Visually, the GNOME UI is great.